1State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China 2Department of Pediatric Emergency, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510623, China 3Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan 430071, China †These authors contributed equally to this work. *Correspondence to:Peiqing Li , Email:annie_129@126.com Hualin Wang , Email:h.wang@wh.iov.cn Yun-Jia Ning , Email:nyj@wh.iov.cn